GAME OF THE WEEK
San Francisco (plus 6 1/2) at Minnesota, 11 a.m.
A great quarterback matchup with the 49ers’ Jimmy Garoppolo against the Vikings’ Kirk Cousins, who were in New England and Washington, respectively, at this time last year. The Vikings believe Cousins is the final piece of their Super Bowl puzzle, but their top-ranked defense that will help them start 1-0.
Vikings 27, 49ers 20.
LOCK OF THE WEEK
Kansas City (plus 3) at L.A. Chargers, 2:05 p.m.
Despite Joey Bosa nursing a foot injury and no home-field advantage while playing at a soccer stadium, we like the Chargers to make an AFC West statement against new Chiefs starting quarterback Patrick Mahomes. Los Angeles started 0-4 last year but will start 5-1 this year.
Chargers 34, Chiefs 17.
UPSET OF THE WEEK
Tennessee (minus 1) at Miami, 11 a.m.
Why are the Titans — 0-4 in the preseason with a new coach (Mike Vrabel) and two new coordinators –giving a point to the Dolphins? We’ll take it. Miami traded receiver Jarvis Landry and moved on from center Mike Pouncey and defensive tackle Ndamukong Suh. But the Titans will wilt in south Florida heat.
Dolphins 17, Titans 13.
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